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title: Functional annotations
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---
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Functional annotation helps bringing biological meaning to genetic sequences. Functional annotation is usually obtained through protein sequence similarity. Indeed, across two organisms, if two sequences are very similar, one can infer that they can encode for the same biological function.
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There are several main parameters that will impact the process of functional annotation:
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- how distant is the species which was actually annotated with experimental data (the reference)
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... | ... | @@ -127,4 +128,17 @@ md5sum -c interproscan-5.65-97.0-bit.tar.gz.md5 |
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# Must return *interproscan-5.65-97.0-bit.tar.gz: OK*
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./interproscan-5.65-97.0/interproscan.sh -cpu 15 -iprlookup -goterms -f TSV -i mtrun.fa -o mtru.tsv
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``` |
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\ No newline at end of file |
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```
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```
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MtrunA17Chr2g0319311.1 45cf42d1c723e145a264cdb6d0420efe 541 Pfam PF01501 Glycosyl transferase family 8 218 515 1.1E-84 T 17-08-2022 IPR002495 Glycosyl transferase
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, family 8 GO:0016757
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MtrunA17Chr2g0319311.1 45cf42d1c723e145a264cdb6d0420efe 541 CDD cd06429 GT8_like_1 216 528 3.86131E-98 T 17-08-2022 - -
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MtrunA17Chr2g0319311.1 45cf42d1c723e145a264cdb6d0420efe 541 PANTHER PTHR32116 GALACTURONOSYLTRANSFERASE 4-RELATED 20 539 0.0 T 17-08-2022 IPR029993 Plan
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t galacturonosyltransferase GAUT GO:0047262
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MtrunA17Chr2g0319311.1 45cf42d1c723e145a264cdb6d0420efe 541 Coils Coil Coil 539 541 - T 17-08-2022 - -
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MtrunA17Chr2g0319311.1 45cf42d1c723e145a264cdb6d0420efe 541 PANTHER PTHR32116:SF63 GALACTURONOSYLTRANSFERASE 12-RELATED 20 539 0.0 T 17-08-2022 - -
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MtrunA17Chr2g0319311.1 45cf42d1c723e145a264cdb6d0420efe 541 SUPERFAMILY SSF53448 Nucleotide-diphospho-sugar transferases 216 539 6.19E-62 T 17-08-2022 IPR0
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29044 Nucleotide-diphospho-sugar transferases -
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MtrunA17Chr2g0319311.1 45cf42d1c723e145a264cdb6d0420efe 541 Gene3D G3DSA:3.90.550.10 Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A 218 536 3.3E-41 T 17-0
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8-2022 IPR029044
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``` |